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Paleogenomic Analysis of 8,500-Year-Old 'Mesolithic' Remains in the Iron Gates Gorge Identifies Genetic Adaptation to Freshwater Diets

📅 April 4, 2026 📰 Nature Communications
Paleogenomic Analysis of 8,500-Year-Old 'Mesolithic' Remains in the Iron Gates Gorge Identifies Genetic Adaptation to Freshwater Diets

In a study published in Nature Communications, geneticists have analyzed the remains of hunter-gatherers from the Iron Gates Gorge on the Danube. They discovered a unique genetic adaptation in the FADS gene cluster, which allowed these populations to efficiently process omega-3 fatty acids from freshwater fish. This is the first evidence of localized genetic selection driven specifically by a riverine ecosystem predating the Neolithic revolution.

The findings indicate that these Mesolithic communities were not merely opportunistic foragers but had developed a highly specialized biological and cultural relationship with the river over millennia. Dr. Sarah Jenkins explained that this 'fish-eater's signature' provides a vital link in understanding how human metabolism evolved in response to diverse post-glacial environments before the widespread adoption of agriculture and dairy.

Original source: Nature Communications