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Genomic Analysis of 12,000-Year-Old 'Trans-Himalayan' Remains Identifies Earliest Genetic Adaptation to Cold-Induced Hypertension

📅 April 8, 2026 📰 Human Genetics
Genomic Analysis of 12,000-Year-Old 'Trans-Himalayan' Remains Identifies Earliest Genetic Adaptation to Cold-Induced Hypertension

A groundbreaking paleogenetic study has uncovered a unique evolutionary trait in the remains of Early Holocene foragers from the Trans-Himalayan region. The analysis identifies the earliest known genetic mutation that provides resistance to cold-induced hypertension, a condition usually common in high-altitude environments where extreme cold restricts blood flow.

The study proves that these ancient populations underwent rapid selection to survive the Post-Glacial Aridity Pulse. By mapping these specific genetic pathways, researchers are gaining new insights into the physiological challenges faced by the first permanent settlers of the Tibetan fringe and their long-term survival strategies.

Original source: Human Genetics